Wnt1 CLIA Kit for Mouse(Mus musculus) | EIAab.comWnt1 CLIA Kit for Mouse(Mus musculus)

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Wnt1 (Gene name),

Proto-oncogene Wnt-1 (Protein name ), WNT1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Wnt1(Int-1;Wnt-1);

Protein name:

Proto-oncogene Wnt-1;

Alternative:

Proto-oncogene Int-1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with PORCN. Interacts with RSPO1, RSPO2 and RSPO3. Interacts with WLS.

Function:

Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. Proeminent role in the induction of the mesencephalon and cerebellum. May play a crucial role in the morphogenesis of the neural tube and/or the early stages of CNS development.

Subcellular Location:

Secreted extracellular space extracellular matrix

Protein Attributes:

Sequence length:

370

Sequence:

50:

100:

150:

200:

250:

300:

350:

370:

WCCHVSCRNC | THTRVLHECL |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P04426

KEGG:

mmu:22408

UniGene:

Mm.1123

SMR:

P04426

Pfam:

PF00110

STRING:

10090.ENSMUSP00000023734

Uniprot:

P04426

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ELISA Kit for Mouse Proto-oncogene Wnt-1

Cat.:

E1414h

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96T

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ELISA Kit for Mouse Proto-oncogene Wnt-1

Cat.:

E1414c

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96T

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ELISA Kit for Mouse Proto-oncogene Wnt-1

Cat.:

E1414m

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96T

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CLIA Kit for Mouse Proto-oncogene Wnt-1

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CLIA Kit for Mouse Proto-oncogene Wnt-1

Cat.:

U1414h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Proto-oncogene Wnt-1

Cat.:

U1414m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Proto-oncogene Wnt-1

Cat.:

P1414Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse Proto-oncogene Wnt-1

Cat.:

P1414Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Proto-oncogene Wnt-1

Protein for Mouse Proto-oncogene Wnt-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact."
Ooyen A.V. , Nusse R.
Cell39:233-240(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: C3H.
2.

"Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene."
Fung Y.-K.T. , Shackleford G.M. , Brown A.M.C. , Sanders G.S. , Varmus H.E.
Mol. Cell. Biol.5:3337-3344(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development."
Gavin B.J. , McMahon J.A. , McMahon A.P.
Genes Dev.4:2319-2332(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Czech II.
5.

"Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development."
Thomas K.R. , Capecchi M.R.
Nature346:847-850(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POSSIBLE FUNCTION
6.

"Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo."
Wilkinson D.G. , Bailes J.A. , McMahon A.P.
Cell50:79-88(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
strain: CBA/Ca.
tissue: Embryo.
7.

"Expression of the proto-oncogene int-1 is restricted to postmeiotic male germ cells and the neural tube of mid-gestational embryos."
Shackleford G.M. , Varmus H.E.
Cell50:89-95(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
strain: ICR.
8.

"The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family."
Tanaka K. , Okabayashi H. , Asashima M. , Perrimon N. , Kadowaki T.
Eur. J. Biochem.267:4300-4311(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PORCN
9.

"Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth."
Lu W. , Yamamoto V. , Ortega B. , Baltimore D.
Cell119:97-108(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
10.

"Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract."
Liu Y. , Shi J. , Lu C.C. , Wang Z.B. , Lyuksyutova A.I. , Song X.J. , Zou Y.
Nat. Neurosci.8:1151-1159(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
11.

"Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression."
Nam J.-S. , Turcotte T.J. , Smith P.F. , Choi S. , Yoon J.K.
J. Biol. Chem.281:13247-13257(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RSPO1; RSPO2 AND RSPO3
12.

"Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation."
Fu J. , Jiang M. , Mirando A.J. , Yu H.-M. , Hsu W.
Proc. Natl. Acad. Sci. U.S.A.106:18598-18603(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH WLS
13.

"Mutations in WNT1 cause different forms of bone fragility."
Keupp K. , Beleggia F. , Kayserili H. , Barnes A.M. , Steiner M. , Semler O. , Fischer B. , Yigit G. , Janda C.Y. , Becker J. , Breer S. , Altunoglu U. , Gruenhagen J. , Krawitz P. , Hecht J. , Schinke T. , Makareeva E. , Lausch E. , more...
Am. J. Hum. Genet.92:565-574(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
14.

"WNT1 mutations in early-onset osteoporosis and osteogenesis imperfecta."
Laine C.M. , Joeng K.S. , Campeau P.M. , Kiviranta R. , Tarkkonen K. , Grover M. , Lu J.T. , Pekkinen M. , Wessman M. , Heino T.J. , Nieminen-Pihala V. , Aronen M. , Laine T. , Kroeger H. , Cole W.G. , Lehesjoki A.E. , Nevarez L. , Krakow D. , more...
N. Engl. J. Med.368:1809-1816(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY

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